29-year-old Israel Aguilera and 52-year-old Francisco Cazares-Olivas were arrested Monday for trying to pick up money from a drug deal.
Investigators say a search of their apartment on South Gammon Road in Madison led to $25,000 dollars in cash and 41 kilograms of cocaine.
"The retail is conservatively estimated at about $4 million worth of cocaine."
Also arrested, 54-year-old Jose Olivas-Lopez, for delivering one kilogram of cocaine.
In a news conference Tuesday, the U.S. attorney for the Western District of Wisconsin and drug enforcement agents called this bust significant.
Assistant Special Agent James Bohn said more arrests may come out of this investigation.
"We will continue to actively pursue this investigation to identify all the members of this conspiracy and this organization."
"I have to say though, that the owners are fabulous and ha they noticed any activity they would have let me know and I hadn't heard a word," says Sue Roessel, who manages the complex where two of the men lived.
She says their references checked out and no one had any clue what was going on inside.
"But then I think it can happen to any of us, no matter where we live in society today there's stuff we don't know about our neighbors."
Because the case is ongoing, officials couldn't give us many details about the investigation or how it got started.
A search of the Wisconsin court system website shows no prior charges for any of the three men.
If convicted, each man faces a minimum of ten years and a maximum of life in prison.