Thursday's game that pits the Milwaukee Brewers (86-66) against the St. Louis Cardinals (67-85) at Busch Stadium should be a competitive matchup based on our computer prediction, which projects a final score of 6-4 in favor of the Brewers. First pitch is at 1:15 PM ET on September 21.

The Cardinals will call on Miles Mikolas (7-12) versus the Brewers and Wade Miley (8-4).

Brewers vs. Cardinals Game Info & Odds

  • When: Thursday, September 21, 2023 at 1:15 PM ET
  • Where: Busch Stadium in St. Louis, Missouri
  • How to Watch on TV: MLB Network
  • Live Stream: Watch this game on Fubo!

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Brewers vs. Cardinals Score Prediction

Our pick for this game is Brewers 6, Cardinals 5.

Total Prediction for Brewers vs. Cardinals

  • Total Prediction: Over 8.5 runs

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Discover More About This Game

Brewers Performance Insights

  • The Brewers are underdogs for the first time in a while, as they have not been listed as underdogs in their last 10 games.
  • When it comes to the over/under, Milwaukee and its foes are 4-6-0 in its previous 10 contests.
  • The Brewers have not covered a spread in any of their past 10 games (one of those contests had a spread).
  • The Brewers have been victorious in 35, or 51.5%, of the 68 contests they have been chosen as underdogs in this season.
  • This season, Milwaukee has come away with a win 30 times in 59 chances when named as an underdog of at least -105 or worse on the moneyline.
  • The moneyline set for this matchup implies the Brewers have a 51.2% chance of coming away with a victory in the contest.
  • Averaging 4.5 runs per game (680 total), Milwaukee is the 18th-highest scoring team in baseball.
  • The Brewers have pitched to a 3.78 ERA this season, which ranks third in baseball.

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Brewers Schedule

Date Opponent Score Pitching Matchup
September 16 Nationals W 9-5 Corbin Burnes vs Trevor Williams
September 17 Nationals L 2-1 Brandon Woodruff vs Patrick Corbin
September 18 @ Cardinals L 1-0 Freddy Peralta vs Adam Wainwright
September 19 @ Cardinals W 7-3 Trevor Megill vs Drew Rom
September 20 @ Cardinals W 8-2 Adrian Houser vs Zack Thompson
September 21 @ Cardinals - Wade Miley vs Miles Mikolas
September 22 @ Marlins - Corbin Burnes vs Johnny Cueto
September 23 @ Marlins - Brandon Woodruff vs Jesús Luzardo
September 24 @ Marlins - Freddy Peralta vs Edward Cabrera
September 26 Cardinals - Wade Miley vs Zack Thompson
September 27 Cardinals - Corbin Burnes vs Miles Mikolas