Padres vs. Giants Predictions & Picks: Odds, Moneyline, Spread - September 25

Monday's game at Oracle Park has the San Diego Padres (77-79) squaring off against the San Francisco Giants (77-79) at 9:45 PM ET (on September 25). Our computer prediction projects a narrow 5-3 win for the Padres, so expect a competitive matchup.

This contest's pitching matchup is set, as the Padres will send Blake Snell (14-9) to the mound, while Logan Webb (10-13) will get the nod for the Giants.

Padres vs. Giants Game Info & Odds

• When: Monday, September 25, 2023 at 9:45 PM ET
• Where: Oracle Park in San Francisco, California
• How to Watch on TV: Fox Sports 1
• Live Stream: Watch this game on Fubo!

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Padres vs. Giants Score Prediction

Our pick for this contest is Padres 5, Giants 4.

Total Prediction for Padres vs. Giants

• Total Prediction: Over 7 runs

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Explore More About This Game

• How to Watch Padres vs Giants

Padres Performance Insights

• In nine games over the last 10 matchups when favored by oddsmakers, the Padres have a record of 8-1.
• When it comes to hitting the over, San Diego and its opponents are 4-6-0 in its last 10 games with a total.
• In their last game with a spread, the Padres failed to cover.
• The Padres have won 64, or 55.7%, of the 115 games they've played as favorites this season.
• San Diego has entered 115 games this season favored by -115 or more and is 64-51 in those contests.
• The moneyline for this contest implies a 53.5% chance of a victory for the Padres.
• San Diego has scored 731 runs (4.7 per game) this season, which ranks 13th in MLB.
• The Padres have a 3.88 team ERA that ranks sixth across all MLB pitching staffs.

Giants Performance Insights

• In five games as the underdog over the last 10 matchups, the Giants have posted a mark of 1-4.
• In its previous 10 matchups with a total posted by sportsbooks, San Francisco and its foes are 4-5-1 when it comes to hitting the over.
• The Giants have had a spread set in one of their past 10 games, and they have come up short of covering the spread each time.
• The Giants have won in 29, or 42.6%, of the 68 contests they have been named as odds-on underdogs this year.
• This season, San Francisco has been victorious 22 times in 56 chances when named as an underdog of at least -105 or worse on the moneyline.
• The moneyline set for this matchup implies the Giants have a 51.2% chance of walking away with the win.
• Averaging 4.3 runs per game (664 total), San Francisco is the 23rd-highest scoring team in MLB.
• The Giants have pitched to a 4.10 ERA this season, which ranks 13th in baseball.

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Padres Schedule

Giants Schedule